XenoSkin H - Ex vivo Dermatomed Skin Squares for in vireo Skin Permentation Tests

Art.No.

H-D20S-1

Unit

Frozen Abdominal Human XenoSkin H - Squares Many different dimensions are available as well as fresh ex vivo dermatomed skin. For fresh ex vivo skin please contact This email address is being protected from spambots. You need JavaScript enabled to view it. .

Description

XenoSkin H is an ex vivo dermatomed human skin squares for in vitro skin permeation tests, skin absorption or penetration safety studies of chemicals, agrochemicals, pharmaceuticals, cosmetics or biocides and pesticides. The squares are used according to OECD 428, OECD 28, COLIPA, SCCP. XenoSkin H are also used for selecting drug candidates for dermal application, characterization of topical dosage forms, quality assessment, selecting a suitable transdermal vehicle. XenoSkin H is an excellent in vitro model for skin absorption studies and is replacing test animals.

Characteristics

• abdominal or face ex vivo skin
• average age donor 45 years
• aproved for absence of HBV, HCV, HIV-1, HIV-2  
• time from surgery to lab < 1.5 hours
• macroscopic examination for absence of scars, surgical markers or pubic hairs
• mean thickness 400 - 600 µm
• in line with 3Rs (Reduce, Refine, Replace), replacing animal tests
• many different sizes available