XenoSkin H - Ex vivo Dermatomed Skin Discs for in vitro Skin Permetation Tests

Art.No.

H-D20D-18

Unit

18mm Ø Disks - Frozen Dermatomed Human Abdominal XenoSkin H

Description

XenoSkin H is an ex vivo dermatomed human skin disc for in vitro skin permeation tests, skin absorption or penetration safety studies of chemicals, agrochemicals, pharmaceuticals, cosmetics or biocides and pesticides. The discs are used according to OECD 428, OECD 28, COLIPA, SCCP. XenoSkin H are also used for selecting drug candidates for dermal application, characterization of topical dosage forms, quality assessment, selecting a suitable transdermal vehicle. XenoSkin H is an excellent in vitro model for skin absorption studies and is replacing test animals.

Characteristics

• abdominal or face ex vivo skin
• average age donor 45 years
• aproved for absence of HBV, HCV, HIV-1, HIV-2  
• time form surgery to lab < 1.5 hours
• macroscopic examination for absence of scars, surgical markers or pubic hairs
• mean thickness 400 - 600 µm
• in line with 3Rs (Reduce, Refine, Replace), replacing animal tests
• many different sizes available